Effect of cognitive reserve on age of symptom onset and rate of cognitive decline in Dominantly Inherited Alzheimer’s Disease

Published in Neurology (Provisionally Accepted), 2025

Research conducted during my internship at Washington University in St. Louis, Institute for Informatics.

The study investigates the role of cognitive reserve in modulating symptom onset and longitudinal cognitive decline in individuals with Dominantly Inherited Alzheimer’s Disease (DIAD). This work contributes to understanding protective factors that may delay clinical manifestation of the disease.

Recommended citation: Llibre-Guerra, J., Lu, R., Clarens, M. F., Liu, I., Renton, A., Ryan, N., Goate, A., Aguillon, D., Allegri, R. F., Benzinger, T., Berman, S., Chhatwal, J., Chrem, P., Vigo, G., Cruchaga, C., Day, G., Farlow, M., Fox, N., Gordon, B., Hassenstab, J., Huey, E., Ibanez, L., Ikeuchi, T., Jucker, M., Lee, J-H., Levey, A., Levin, J., Martins, R., Niimi, Y., Perrin, R., Rosa-Neto, P., Sanchez-Valle, R., Schofield, P., Wang, G., Li, Y., Xiong, C., Morris, J., Karch, C., Daniels, A., McDade, E., & Bateman, R. (2025). Effect of cognitive reserve on age of symptom onset and rate of cognitive decline in Dominantly Inherited Alzheimer's Disease. Neurology. (Provisionally Accepted).